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A literature review as an aid to identify strategies for mitigating ostreid herpesvirus 1 in Crassostrea gigas hatchery and nursery systems ArchiMer
Rodgers, Chris; Arzul, Isabelle; Carrasco, Noèlia; Furones Nozal, Dolores.
An understanding of husbandry strategies and any associated risk factors is important for designing management control measures that can reduce mortality in Pacific oysters, Crassostrea gigas, caused by ostreid  herpesvirus 1 (OsHV-1). The type of culture facility can be considered in relation to the potential pathways that could lead to the entry of a pathogen and its survival. In addition, the animal host (e.g. age, physiological state,  selective breeding programmes), husbandry procedures (e.g. stocking density), the pathogen itself (e.g. pathogenicity, virulence) and environmental effects (e.g. temperature) represent other relevant interconnected factors. However, all these factors provide valuable background information for outlining the mitigation...
Tipo: Text Palavras-chave: Crassostrea gigas; Husbandry; Management strategies; Ostreid herpesvirus 1; Oyster herpesvirus; Risk factors.
Ano: 2019 URL: https://archimer.ifremer.fr/doc/00474/58581/61146.pdf
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A study of risk factors associated with the prevalence of Cryptosporidium in villages around Lake Atitlan, Guatemala BJID
Laubach,H. E.; Bentley,C. Z.; Ginter,E. L.; Spalter,J. S.; Jensen,L. A..
Cryptosporidium parvum is an endemic, zoonotic coccidian parasitosis that is highly prevalent in third-world countries where waterborne fecal contamination of food and drink or person-to-person contact with oocysts are the most common methods of transmission of the enteric protozoan. This type of transmission of the parasite made the villages around Lake Atitlan, Guatemala a unique site to compare environmental risk factors with the level of Cryptosporidium infections in the local residents. The study was carried out in two villages, San Antonio Palopo and Santa Catarina Palopo, located in the highlands above the shores of the lake. Smears from stool specimens of patients with gastroenteritis were processed using Kinyoun's modified acid-fast stain and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryptosporidium; Disease transmission; Guatemala; Risk factors; Lake-water.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000400008
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Additional value of a combined genetic risk score to standard cardiovascular stratification Genet. Mol. Biol.
Pereira,Andreia; Mendonca,Maria Isabel; Borges,Sofia; Sousa,Ana Célia; Freitas,Sónia; Henriques,Eva; Rodrigues,Mariana; Freitas,Ana Isabel; Guerra,Graça; Freitas,Carolina; Pereira,Décio; Brehm,António; Reis,Roberto Palma Dos.
Abstract The utility of genetic risk scores (GRS) as independent risk predictors remains inconclusive. Here, we evaluate the additive value of a multi-locus GRS to the Framingham risk score (FRS) in coronary artery disease (CAD) risk prediction. A total of 2888 individuals (1566 coronary patients and 1322 controls) were divided into three subgroups according to FRS. Multiplicative GRS was determined for 32 genetic variants associated to CAD. Logistic Regression and Area Under the Curve (AUC) were determined first, using the TRF for each FRS subgroup, and secondly, adding GRS. Different models (TRF, TRF+GRS) were used to classify the subjects into risk categories for the FRS 10-year predicted risk. The improvement offered by GRS was expressed as Net...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coronary artery disease; Genetic risk score; Framingham score; Risk prediction; Risk factors.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572018000500766
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Analysis of risk factors and clinical manifestations associated with Clostridium difficile disease in Serbian hospitalized patients BJM
Predrag,Stojanović.
Abstract Clostridium difficile is the leading cause of infectious diarrhoea in hospitalized patients. The aim of this study was to determine the risk factors important for the development of hospital-acquired Clostridium difficile-associated disease and clinical manifestations of Clostridium difficile-associated disease. The clinical trial group included 37 hospitalized patients who were selected according to the inclusion criteria. A control group of 74 hospitalized patients was individually matched with cases based on hospital, age (within 4 years), sex and month of admission.Clostridium difficile-associated disease most commonly manifested as diarrhoea (56.76%) and colitis (32%), while in 8.11% of patients, it was diagnosed as pseudomembranous colitis,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Clostridium difficile; Hospital-acquired diarrhoea; Risk factors; Serbia.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400902
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Angina pectoris in patients with HIV/AIDS: prevalence and risk factors BJID
Zirpoli,Josefina Cláudia; Lacerda,Heloisa Ramos; Albuquerque,Valéria Maria Gonçalves de; Albuquerque,Maria de Fátima Pessoa Militão de; Miranda Filho,Demócrito de Barros; Monteiro,Verônica Soares; Barros,Isly Lucena de; Arruda Junior,Evanízio Roque de; Montarroyos,Ulisses Ramos; Ximenes,Ricardo Arraes de Alencar.
INTRODUCTION: The incidence of ischemic heart disease is higher in patients with HIV/AIDS. However, the frequency of angina pectoris in these patients is still not known. Literature about this subject is still scarce. OBJECTIVE: To evaluate the prevalence of angina pectoris and risk factors for coronary disease and to examine the association between traditional risk factors and HIV-related risk factors and angina pectoris. METHOD: An epidemiological cross-sectional study, analyzed as case-control study, involving 584 patients with HIV/AIDS. Angina pectoris was identified by Rose questionnaire, classified as definite or possible. Information regarding risk factors was obtained through a questionnaire, biochemical laboratory tests, medical records and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acquired immunodeficiency; Syndrome; Angina pectoris; Coronary disease; Risk factors.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100001
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Angiotensin II type 1 receptor A1166C GENE polymorphism and essential hypertension in San Luis Biocell
Lapierre,Alicia Viviana; Arce,María Elena; Lopez,José Raúl; Ciuffo,Gladys María.
Essential hypertension is considered a multifactorial trait resulting from a combination of environmental and genetic factors. The angiotensin II type 1 receptor mediates the vasoconstrictor and growthpromoting effects of Ang II. The A1166C polymorphism of the AT1 receptor gene may be associated with cardiovascular phenotypes, such as high arterial blood pressure, aortic stiffness, and increased cardiovascular risk. We investigated the association between this A1166C polymorphism and hypertension in hypertense and normotense subjects from San Luis (Argentina) by mismatch PCR-RFLP analysis. Hypertense patients exhibited significant increases in lipid related values and body mass index. The frequency of occurrence of the C1166 allele was higher among...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin II; A1166C polymorphism; Risk factors; RAS system; Pharmacogenetics.
Ano: 2006 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452006000300005
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Assessment of health risks and local intervention associated to living together with dogs and cats, developed at Jardim Parana, district of Brasilandia. São Paulo, Sp,- Brazil, 2003 MV&Z
Gomes, Luciana Hardt; de Almeida, Marilene Fernandes; Paranhos, Noêmia Tucunduva; Garcia, Rita de Cássia; Nunes, Vânia de Fátima Plaza; Montenegro Neto, Hildebrando; Cardoso, Sônia Maria Sodré.
Objective: To carry out a situational diagnosis of interactions among man, animal and environment, to test intervention and control model in dogs and cats and lo make local population aware in order to improve human and animal health. Material and Method: The project "Evaluation of risks to the heath and local intervention associated to living together with dogs and cats" was carried out in the area invaded in Jardim Paraná, District of Brasilândia, São PauLo city, Brazil, in 2003 by the Center of Zoonosis Control of the São Paulo Municipality. Animal census, vaccinations, treatment of ectoparasitosis and endoparasitosis, animal register, animal sterilization, serological and soil examinations and removal of animals was carried through. Forty seven percent...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Zoonoses; Community health; Local planning; Animal health; Environment; Risk factors; Human; Animal; Interactions; Intervention; Population control; Sterilization; Dogs; Cats Zoonosis; Planificación en salud comunitaria; Estrategias locales; Salud animal; Medio ambiente y salud publica; Factores de riesgo; Hombres; Animales; Vínculo ser humano-animal; Estudios de intervención; Regulación de la población zoonoses; Planejamento em saúde comunitária; Estratégias locais; Saúde animal; Meio ambiente e saúde pública; Fatores de risco; Homens; Animais; Vínculo homem-animal; Estudos de intervenção; Controle da população; Esterilização reprodutiva; Cães; Gatos.
Ano: 2003 URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3262
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Assessment of sexual risk behaviors and perception of vulnerability to sexually transmitted diseases/acquired immunodeficiency syndrome in women, 1999-2012: a population based survey in a medium-sized Brazilian city BJID
Mesenburg,Marilia Arndt; Muniz,Ludmila Correa; Silveira,Mariângela Freitas.
Sexual behavior is a key factor for susceptibility to sexually transmitted diseases. An evaluation of the sexual behavior of women at reproductive age was conducted in 1999. A replication of this study aims to evaluate the current situation and identify changes in sexual behavior, 13 years later. This is a population-based cross-sectional study, conducted with 1071 women in Pelotas, Brazil. Compared to the 1999 study, a 14% increase in early sexual debut and an 8% decrease in the non-use of condoms were observed in 2012. The proportion of women who reported anal sex doubled between these periods. There was no trend of increase or decrease in the prevalence of behaviors with distinct patterns being observed for each of them. Reduction of non-use of condoms...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sexually transmitted diseases; Behavior; Risk factors; Women.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400414
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Association of MDR1 gene polymorphisms with the risk of hepatocellular carcinoma in the Chinese Han population BJMBR
Gao,Jian.
The multidrug resistance 1 gene (MDR1) is an important candidate gene for influencing susceptibility to hepatocellular carcinoma (HCC). The objective of the present study was to evaluate the association ofMDR1 polymorphisms with the risk of HCC in the Chinese Han population. A total of 353 HCC patients and 335 healthy subjects were enrolled in the study. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), created restriction site-PCR (CRS-PCR) and DNA sequencing methods were used to identify MDR1 gene polymorphisms. Two allelic variants (c.335T>C and c.3073A>C) were detected. The CC genotype of the c.335T>C polymorphism was associated with an increased risk of developing HCC compared to the TT genotype (OR = 2.161, 95%CI...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatocellular carcinoma; Multidrug resistance 1 gene; Single nucleotide polymorphisms; Susceptibility; Risk factors.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000300311
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Bacteremic pneumococcal pneumonia: serotype distribution, antimicrobial susceptibility, severity scores, risk factors, and mortality in a single center in Chile BJID
Fica,Alberto; Bunster,Nicolás; Aliaga,Felipe; Olivares,Felipe; Porte,Lorena; Braun,Stephanie; Dabanch,Jeannette; Hormázabal,Juan Carlos; Hernández,Antonio; Benavides,María Guacolda.
AIMS:Bacteremic pneumococcal pneumonia (BPP) is a severe condition. To evaluate seasonal distribution, mortality, serotype frequencies, antimicrobial susceptibility, and different severity scores among patients with BPP.PATIENTS AND METHODS:Patients were identified by laboratory data and restricted to adulthood. Standard methods were used for serotyping and antimicrobial susceptibility. Risk factors were analyzed by univariate and multivariate methods. Severity scores (APACHE II, CURB-65 and CAP PIRO) were compared using ROC curves.RESULTS:Sixty events of community-acquired BPP occurred between 2005 and 2010. A seasonal pattern was detected. Mean age was 72.1 years old (81.4% >60 years). All had a predisposing factor. Previous influenza (3.3%) or...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Streptococcus pneumoniae; Bacteremia; Serotyping; Microbial drug resistance; Risk factors; Mortality; Elderly; CURB-65; APACHE II; PIRO.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200115
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Bloodstream infections caused by ESBL-producing E. Coli and K. pneumoniae: risk factors for multidrug-resistance BJID
Serefhanoglu,Kivanc; Turan,Hale; Timurkaynak,Funda Ergin; Arslan,Hande.
This prospective case-control study was conducted from October 2003 to June 2007 to evaluate risk factors for multidrug resistance among extended-spectrum-b-lactamase-producing Escherichia coli and Klebsiella spp. (ESBL-EK) isolates in blood cultures. All adult patients (>18 years old) whose blood cultures grew ESBL-EK during the study period were included. An ESBL-EK isolate was defined as MDR if it was resistant to at least one member of following two classes of antibiotics: aminoglycosides (amikacin, gentamicin, or netilmycin) and fluoroquinolones (ofloxacin, or ciprofloxacin). Case patients were those with a MDR ESBL-EK isolate, and control patients were those with a non-MDR ESBL-EK isolate. A total of 94 bloodstream infections, including 37 (39,4%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: ESBLs; Multidrug resistance; Risk factors.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600003
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Bone mineral density in young women of the city of São Paulo, Brazil: correlation with both collagen type I alpha 1 gene polymorphism and clinical aspects BJMBR
Barros,E.R.; Kasamatsu,T.S.; Ramalho,A.C.; Hauache,O.M.; Vieira,J.G.H.; Lazaretti-Castro,M..
Osteoporosis is a multifactorial disease with great impact on morbidity and mortality mainly in postmenopausal women. Although it is recognized that factors related to life-style and habits may influence bone mass formation leading to greater or lower bone mass, more than 85% of the variation in bone mineral density (BMD) is genetically determined. The collagen type I alpha 1 (COLIA1) gene is a possible risk factor for osteoporosis. We studied a population of 220 young women from the city of São Paulo, Brazil, with respect to BMD and its correlation with both COLIA1 genotype and clinical aspects. The distribution of COLIA1 genotype SS, Ss and ss in the population studied was 73.6, 24.1 and 2.3%, respectively. No association between these genotypes and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: COLIA1; Bone mineral density; Risk factors; Polymorphism; Osteoporosis.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800005
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Brucella canis infection in dogs attended in veterinary clinics from patos, Paraíba state, Brazil BJM
Fernandes,Annielle Regina Fonseca; Azevedo,Sérgio Santos de; Piatti,Rosa Maria; Pinheiro,Eliana Scarcelli; Genovez,Margareth Élide; Azevedo,Adílio Santos de; Batista,Carolina de Sousa Américo; Alves,Clebert José.
To determine the frequency of anti-Brucella canis antibodies in dogs attended in veterinary clinics from Patos, Paraíba State, Brazil, as well as to identify risk factors and to isolate and identify the agent, 193 dogs were used. Agar gel immunodiffusion test (AGID) was used to detect B. canis antibodies in sera. Isolation of B. canis was carried out in blood and bone marrow from seropositive animals. Six animals tested seropositive in AGID, resulting in a frequency of 3.11%. B. canis was isolated from bone marrow of one seropositive animal, with confirmation by PCR. Lack of cleaning of the dog's environment was identified as risk factor (odds ratio = 7.91). This is the first report of isolation of B. canis in dogs from the Northeast region of Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bacterial diseases; Canine brucellosis; Prevalence; Risk factors; Microbiological culture.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400023
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Canine visceral leishmaniasis in the Northeast Region of Brazil J. Venom. Anim. Toxins incl. Trop. Dis.
Brito,Flávio Gonçalves; Langoni,Helio; Silva,Rodrigo Costa da; Rotondano,Tereza Emmanuelle de Farias; Melo,Marcia Almeida de; Paz,Giselle Souza da.
Abstract Background Visceral leishmaniasis (VL) is a zoonosis that affects dogs and other mammals, including humans. Contact with dogs is a major risk factor for humans. This disease is endemic in several regions of Brazil. The aim of this study was to determine the prevalence of Leishmania spp. infection in dogs and to correlate it with possible risk factors. Methods Blood samples were collected from 391 dogs of different ages, breeds, and both genders, coming from Campina Grande, Paraíba state, Brazil. An epidemiological questionnaire was employed in order to identify risk factors associated with the disease. Serological tests were performed using indirect immunofluorescence, enzyme-linked immunosorbent assay (ELISA S7®) and polymerase chain...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Kala-azar; Diagnosis; Dog; Zoonosis; Risk factors.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992016000100311
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Characteristics associated with anti-HCV serological markers in prisoners in the state of Paraná, Brazil: a case-control study BJID
Silva,Tânia Maria Pazin Marques; Ferreto,Lirane Elize Defante; Follador,Franciele Ani Caovilla; Vieira,Ana Paula; Yamada,Roberto Shigueyasu; Lucio,Léia Carolina; Titon,Joana Perotta; Torres,Renata Himovski; Amaral,Greicy Cézar do; Coelho,Harnoldo Colares.
ABSTRACT Background: The prison system in Paraná, Brazil, is experiencing serious problems related to the increasing number of prisoners. Control of hepatitis C virus (HCV) has become more intense because the incarcerated population is considered a high-risk group for contagious diseases due to the favorable conditions found in prisons for the spread of these morbidities. The objective of this study was to identify features associated with hepatitis C infection among male prisoners in correctional institutions of Paraná state, Brazil. Methods: This was a case-control study (27 cases and 54 controls) of men incarcerated in 11 penitentiaries in Paraná, Brazil. Information was obtained through a questionnaire in a cross-sectional epidemiological survey on...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Risk factors; Prisoners.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000300173
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Clinical risk factors for Clostridium difficile-associated diseases BJID
Cho,Sung Min; Lee,Jae Joon; Yoon,Hee Jung.
Many factors appear to influence the chance of acquiring Clostridium difficile (C. difficile) infection, and an accurate identification of risk factors could be beneficial in many ways. Thus, in the present study, clinical risk factors for C. difficile-associated disease (CDAD) in Korea were identified. A total of 93 patients who met the inclusion criteria and 186 age/gender/ward/admission period-matched control patients were included in this study. Statistically significant associations were found with presence of chronic lung diseases (odds ratio [OR], 3.41; 95% confidence interval [CI], 1.25-9.32; p = 0.017), presence of ileus (OR, 10.05; 95% CI, 2.42-41.80; p = 0.001), presence of intensive care unit (ICU) stay (OR, 9.79; 95% CI, 3.03-31.68; p <...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Risk factors; Clostridium difficile-associated; Diseases.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300007
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Comparing hospital infections in the elderly versus younger adults: an experience in a Brazilian University Hospital BJID
The elderly population will grow rapidly over the next 25 years, however there is little information about hospital infections in this group of patients in Brazil. We examined the prevalence of nosocomial and community infections in elderly (>65 years) patients and their relationship with intrinsic and extrinsic risk factors in a Brazilian University Hospital. A total of 155 hospitalized elderly patients were evaluated, and clinical and demographic information about each patient was obtained from hospital records. The rates of nosocomial and community infections were 16.1% and 25.6%, respectively. When the elderly group with and without nosocomial infections was analyzed, practically all the risk factors considered (use of antibiotics, invasive devices,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Elderly; Nosocomial infections; Risk factors; Brazilian hospitals; Infection control.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300006
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Comparison of risk factors among blood donors, volunteers and replacement individuals, infected or not by hepatitis C virus J. Venom. Anim. Toxins incl. Trop. Dis.
Felippe,MJDB; Meira,DA.
Hepatitis C is transmitted primarily parenterally by contaminated blood and is often associated with: intravenous drug abuse, invasive procedures, blood transfusions, acupuncture, tattooing, and alcohol and tobacco use. This study aimed to quantify and evaluate the risk factors among blood donors, volunteer blood donors and replacement individuals, infected or not by the C virus. The main transmission routes of C virus were identified in 55 men and 25 women (GI) monitored by the Ambulatory Unit of the Department of Tropical Diseases, Botucatu Medical School, and in 24 men and 26 women (GII), all active blood donors at the Bauru State Hospital Transfusional Agency. Both groups were similar in: tobacco and alcohol consumption, sexual behavior, tattooing and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis C; Risk factors; Blood donors; Injectable drugs; Tobacco; Alcohol; Marijuana; Sexual behavior.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000100010
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Dialysis, time and death: comparisons of two consecutive decades among patients treated at the same Brazilian dialysis center BJMBR
De-Lima,J.J.G.; da-Fonseca,J.A.; Godoy,A.D..
The survival of hemodialysis patients is likely to be influenced not only by well-known risk factors like age and comorbidity, but also by changes in dialysis technology and practices accumulated along time. We compared the survival curves, dialysis routines and some risk factors of two groups of patients admitted to a Brazilian maintenance hemodialysis program during two consecutive decades: March 1977 to December 1986 (group 1, N = 162) and January 1987 to June 1997 (group 2, N = 237). The median treatment time was 22 months (range 1-198). Survival curves were constructed using the Kaplan-Meier method and compared using the log-rank method. The Cox proportional hazard regression model was used to investigate the more important variables associated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic renal failure; Hemodialysis; Kaplan-Meier survival curves; Risk factors.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000300007
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Different methods of calculating ankle-brachial index in mid-elderly men and women: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) BJMBR
Miname,M.; Bensenor,I.M.; Lotufo,P.A..
The ankle-brachial index (ABI) is a marker of subclinical atherosclerosis related to health-adverse outcomes. ABI is inexpensive compared to other indexes, such as coronary calcium score and determination of carotid artery intima-media thickness (IMT). Our objective was to identify how the ABI can be applied to primary care. Three different methods of calculating the ABI were compared among 13,921 men and women aged 35 to 74 years who were free of cardiovascular diseases and enrolled in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). The ABI ratio had the same denominator for the three categories created (the highest value for arm systolic blood pressure), and the numerator was based on the four readings for leg systolic blood pressure: the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Peripheral artery disease; Risk factors; Atherosclerosis; Cardiovascular risk; Primary care.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001200701
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